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()ng who vape e more likely to use mijuana, according to a study published Monday. The findings, rerchers say, the theory that nicotine rewires the developing b, changing how respond to and crave addictive substances.

When a ng b is ed to an addictive substance such as nicotine, it “tends to be sensitized to substances; it tends to seek a thrilling, rewding setion,” sd Chadi. “And so substances like mijuana become more ealing.”
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The rerch, published in the medical journal JAMA Pediatrics, analyzed more than 20 pre-eisting studies of s 10 to . The re found that the odds of mijuana use were 3.5 s higher in who vaped comped to those who didn’t.
    That link suggests that “ rey need to be con in the broad category of addictive and hmful substances,” sd Chadi, who is an at the .
    “We can’t think of as a less-hmful alternative to with adolescents,” he sd, in pt because “just like , increase r risk of using mijuana, and mijuana, we k, has several implications and negative consequences in adolescents.”
    Teen use of the is associated with declines in and mental function that persist into adulthood, according to some studies, and mijuana has been linked to psychosis, which can and delusions.

    Re ed at correlation, not cation

    Studies d in the re ed for correlation, not cation, meaning that rerchers couldn’t prove that directly caused increases in use. But when it comes to figuring out why mijuana use consistently increased in those who vaped, Chadi sd “it’s hd for me to find a better eplanation.”
    research says - CNN
    “A able hypothesis,” he sd, “is that use might cause at least a pt of that increased risk of using mijuana.”
    Most of the 21 studies d in the re adjusted for , , and socioeconomic , sd Chadi. Rerch s best “by adjusting of those fs, and repeating the same study in different pts of the and using different s,” he sd.
    “The more s do that, the less s have of finding an association that’s not , that’s not true,” he added.
    Comped to ng adults s 18 to , teens nger than 17 were also more likely to use mijuana if they vaped, the re found. “The seemed to be stronger in nger versus ,” sd Chadi. That makes sense, he sd, because “a nger b is more vulnerable to the effects of substances in general.”
    If a nger teen is ed to , “ would epect that would be a higher risk of them using mijuana, versus an adolescent or ng adult who might have a more developed b and might not be as sensitive to the negative effects of nicotine,” he added.

    Developing bs e more vulnerable, eperts say

    Eperts have previously wned that nicotine changes the brain, interfering with development up until about 26 yes .
    Vaping linked to marijuana use in young people
    Leventhal, of the , , and Addiction Laboratory at the , told CNN elier this ye that “’s concern that the adolescent b be more vulnerable to the addictive effects of nicotine.”
    He added that “the circuits underlying pleasure and the pursuit of novel, enjoyable eperiences develop much faster than the circuits that promote decision making, impulse control and rational .”
    The nation’s top has also weighed in. Former General Dr. Vivek H. Murthy, in a 2016 report, sd that “comped with adults, the b of th and ng adults is more vulnerable to the negative consequences of nicotine eposure.”

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    The link between nicotine and mijuana is not . A study published last ye, for eample, found that teens who vaped and used hookah were up to four s more likely to use mijuana later.
      Some teens put into , with almost 1 in 11 middle and students saying they have vaped mijuana, according to a report published last ye.
      While more than two dozen states have legalized marijuana in some way — either for medical or recreational use — Chadi wned that the is not risk-free, especiy in ng . It can affect memory, lening and higher-level functioning, he sd, and “those e risks that don’t go away.”

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